Rai Classification System


Low risk
Stage 0
Elevated lymphocyte count (lymphocytosis) greater than 5000/mm 3 (in blood and bone marrow)
Intermediate risk
StageI

Lymphocytosis with enlarged lymph nodes

stageII

Lymphocytosis with enlarged spleen and/or liver (may or may not have enlarged lymph nodes)

High risk
StageIII

Lymphocytosis with anemia (hemoglobin<11G/dl)

StageIV

Lymphocytosis with low platelet count (platelets<100,000)
(Both stage III & IV may or may not have enlarged lymph nodes, spleen and/or liver)